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Low Dose Naltrexone (LDN)

What Is Low-Dose Naltrexone?

Naltrexone is an FDA-approved medication traditionally used in higher doses to manage addiction. When prescribed at much lower doses, typically 1.5 mg to 4.5 mg, it is referred to as Low Dose Naltrexone (LDN). In this form, LDN interacts differently with the body, showing potential benefits in areas such as immune regulation, inflammation control, brain health and cellular protection.

At Las Colinas Pharmacy in Irving, TX, we specialize in preparing customized compounded LDN formulations, tailored to meet individual needs.

LDN and Anti-Aging Support

While research on LDN continues to grow, many in the integrative and functional medicine communities are exploring its role in healthy aging and longevity.

Potential Benefits of LDN in the Anti-Aging Realm:

  • Regulation of Inflammation – Chronic inflammation is linked to many age-related conditions. LDN may help modulate the body’s inflammatory response.
  • Immune System Balance – By gently influencing immune activity, LDN may support resilience and balance within the immune system and protect against age-related  changes.
  • Cellular Repair & Regeneration – Studies suggest LDN may encourage endorphin release and cellular signaling pathways tied to pain, inflammation, healing and tissue repair.
  • Brain & Cognitive Health – LDN is being studied for its potential neuroprotective properties, which may support memory, focus, and long-term brain function.
  • Mood & Sleep Support – Improved endorphin levels may contribute to better sleep quality, mood stability, and emotional well-being—all key components of healthy aging.

Compounded LDN at Las Colinas Pharmacy

Since LDN is not commercially available in low doses, it must be prepared by a compounding pharmacy. At Las Colinas Pharmacy, we create LDN in a variety of forms based on your provider’s prescription, including:

  •     Capsules in customized strengths
  •     Oral suspensions for easy dosing adjustments
  •     Sublingual drops or lozenges for rapid absorption

By offering flexible formulations and precise dosing, we help patients and providers incorporate LDN into individualized wellness and anti-aging plans.

Partnering With Providers for Longevity

LDN is not a “one-size-fits-all” therapy. At Las Colinas Pharmacy, we work closely with healthcare providers to help with prescribing, accurate dosing, and ongoing monitoring. This collaborative approach allows LDN to be part of a comprehensive anti-aging strategy that may include nutrition, lifestyle, and other therapies.

Interested in learning more about Low Dose Naltrexone and its potential role in anti-aging and wellness? Contact Las Colinas Pharmacy in Irving, TX to speak with our compounding experts.

Low Dose Naltrexone (LDN) FAQs

Standard naltrexone is usually prescribed at 50-100 mg or more for addiction treatment. In contrast, LDN is typically prescribed at 1.5–4.5 mg. At these lower doses, it works very differently in the body—intermittently blocking opioid receptors in a way that stimulates endorphin release, supports immune balance, and may help regulate inflammation.

LDN is gaining attention in the longevity field because it may influence cellular repair, immune resilience, and inflammation control, all of which are central to aging. Researchers and clinicians are studying its potential role in supporting cognitive function, healthy metabolism, and long-term vitality.

No. LDN is not an overnight solution and is usually part of a comprehensive anti-aging plan that may include nutrition, exercise, stress management, and other therapies. Its benefits are often gradual, with many patients noticing improvements in sleep, energy, or mood within a few months.

LDN is not suitable for patients taking opioid-based pain medications, since it can interfere with their effects. This is why it’s important to have a prescription from your healthcare provider and ongoing pharmacist guidance to help ensure safe use.

Every person is different, but many report noticing changes such as better sleep or improved energy within 6–12 weeks. Because LDN works subtly by influencing the body’s natural processes, benefits often become more noticeable over time.

LDN is generally well-tolerated, especially compared to the higher doses of naltrexone used for addiction treatment. Some patients may experience mild, temporary side effects when starting therapy, including vivid dreams, difficulty sleeping, or mild digestive changes. These effects often improve as the body adjusts or when the dosage is slightly modified. Serious side effects are uncommon, but because every patient is unique, it’s important to work with your healthcare provider and compounding pharmacist to monitor your response and adjust therapy as needed.

LDN is not available in commercially manufactured doses. A compounding pharmacy like Las Colinas Pharmacy can provide precisely tailored formulations based on your provider’s prescription, whether that means adjusting the strength, removing unwanted additives, or creating a form that fits your preferences.

Still curious about LDN and its role in anti-aging and wellness?

Contact Las Colinas Pharmacy in Irving, TX, to speak with our compounding experts and explore whether LDN may be right for you.

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